RAD50 抗体
(1 reference)Quick Overview for RAD50 抗体 (ABIN6146634)
抗原
See all RAD50 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- A synthetic peptide of human Rad50
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亚型
- IgG
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anti-RAD50 Homolog (S. Cerevisiae) (RAD50) antibody
RAD50 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 228-359) antibodyRAD50 适用: 人, 大鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3D2G10 unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 1-100) antibodyRAD50 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (Internal Region) antibodyRAD50 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 228-359) antibodyRAD50 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5A8E5 unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 1-234) antibodyRAD50 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) antibodyRAD50 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 817-872) antibodyRAD50 适用: 人, 小鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 700-750) antibodyRAD50 适用: 人, 小鼠, Cow, 兔, 犬 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 631-793) antibodyRAD50 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
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: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
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- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
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别名
- RAD50
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背景
- The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.,RAD50,NBSLD,RAD502,hRad50,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,RAD50
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分子量
- 138 kDa/153 kDa/154 kDa
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基因ID
- 10111
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UniProt
- Q92878
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途径
- DNA Damage Repair, Protein targeting to Nucleus
抗原
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