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RAD18 抗体 (AA 216-495)

This anti-RAD18 antibody is a 兔 多克隆 antibody detecting RAD18 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6146629
发货至: 中国

Quick Overview for RAD18 抗体 (AA 216-495) (ABIN6146629)

抗原

See all RAD18 抗体
RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAD18 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 216-495

    序列

    INKHLDSCLS REEKKESLRS SVHKRKPLPK TVYNLLSDRD LKKKLKEHGL SIQGNKQQLI KRHQEFVHMY NAQCDALHPK SAAEIVREIE NIEKTRMRLE ASKLNESVMV FTKDQTEKEI DEIHSKYRKK HKSEFQLLVD QARKGYKKIA GMSQKTVTIT KEDESTEKLS SVCMGQEDNM TSVTNHFSQS KLDSPEELEP DREEDSSSCI DIQEVLSSSE SDSCNSSSSD IIRDLLEEEE AWEASHKNDL QDTEISPRQN RRTRAAESAE IEPRNKRNRN

    交叉反应

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 216-495 of human Rad18 (NP_064550.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Guo, He, Liu, Liang, Li, Cai, Lan, Zhou, Wang, Lei: "Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice." in: Journal of cellular and molecular medicine, Vol. 22, Issue 10, pp. 4863-4874, (2018) (PubMed).

  • 抗原

    RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

    别名

    RAD18

    背景

    The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.,RAD18,RNF73,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,RAD18

    分子量

    56 kDa

    基因ID

    56852

    UniProt

    Q9NS91
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