RAD18 抗体 (AA 216-495)
Quick Overview for RAD18 抗体 (AA 216-495) (ABIN6146629)
抗原
See all RAD18 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 216-495
-
序列
- INKHLDSCLS REEKKESLRS SVHKRKPLPK TVYNLLSDRD LKKKLKEHGL SIQGNKQQLI KRHQEFVHMY NAQCDALHPK SAAEIVREIE NIEKTRMRLE ASKLNESVMV FTKDQTEKEI DEIHSKYRKK HKSEFQLLVD QARKGYKKIA GMSQKTVTIT KEDESTEKLS SVCMGQEDNM TSVTNHFSQS KLDSPEELEP DREEDSSSCI DIQEVLSSSE SDSCNSSSSD IIRDLLEEEE AWEASHKNDL QDTEISPRQN RRTRAAESAE IEPRNKRNRN
-
交叉反应
- 人
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 216-495 of human Rad18 (NP_064550.3).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
-
: "Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice." in: Journal of cellular and molecular medicine, Vol. 22, Issue 10, pp. 4863-4874, (2018) (PubMed).
-
: "Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice." in: Journal of cellular and molecular medicine, Vol. 22, Issue 10, pp. 4863-4874, (2018) (PubMed).
-
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
-
别名
- RAD18
-
背景
- The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.,RAD18,RNF73,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,RAD18
-
分子量
- 56 kDa
-
基因ID
- 56852
-
UniProt
- Q9NS91
抗原
-