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RAD18 抗体 (C-Term)

RAD18 适用: 人 WB, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2452086
发货至: 中国
  • 抗原 See all RAD18 抗体
    RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
    抗原表位
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 52
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    • 22
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 45
    • 7
    克隆类型
    • 38
    • 14
    多克隆
    标记
    • 34
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This RAD18 antibody is un-conjugated
    应用范围
    • 30
    • 16
    • 9
    • 8
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应 (详细)
    Not reactive to mouse Rad18
    纯化方法
    Affinity purified with His-tagged Rad18 protein affinity column
    免疫原
    GST-fusion protein containing 113 carboxyl terminal of human Rad18
    亚型
    IgG
    Top Product
    Discover our top product RAD18 Primary Antibody
  • 应用备注
    1) Western blotting: 1,000 fold dilution
    2) Indirect immunofluorescence staining
    3) Immunoprecipitation
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, 50 % glycerol
    储存液
    Azide free
    储存条件
    -20 °C
  • Watanabe, Tateishi, Kawasuji, Tsurimoto, Inoue, Yamaizumi: "Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination." in: The EMBO journal, Vol. 23, Issue 19, pp. 3886-96, (2004) (PubMed).

    Miyase, Tateishi, Watanabe, Tomita, Suzuki, Inoue, Yamaizumi: "Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination." in: The Journal of biological chemistry, Vol. 280, Issue 1, pp. 515-24, (2004) (PubMed).

    Tateishi, Sakuraba, Masuyama, Inoue, Yamaizumi: "Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 14, pp. 7927-32, (2000) (PubMed).

  • 抗原
    RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
    别名
    Rad18 (RAD18 产品)
    别名
    RNF73 antibody, 2810024C04Rik antibody, Rad18sc antibody, zgc:55577 antibody, RAD18 antibody, DDBDRAFT_0218120 antibody, DDBDRAFT_0304878 antibody, DDB_0218120 antibody, DDB_0304878 antibody, DKFZp469H0810 antibody, RAD18, E3 ubiquitin protein ligase antibody, RAD18 E3 ubiquitin protein ligase antibody, E3 ubiquitin-protein ligase RAD18 antibody, E3 ubiquitin-protein ligase antibody, DNA repair protein and ATPase antibody, C3HC4-type zinc finger-containing protein antibody, RAD18 antibody, Rad18 antibody, rad18 antibody
    背景
    The Rad6-Rad18 pair of genes plays a critical role in post-replication repair of damaged DNA. Rad6 protein functions as an E2 enzyme and Rad18 (495 aa, 56 kDa) as an ubiquitine ligase (E3) which ubiquitinates PCNA. Rad18 recruits translesion DNA polymerases to damaged DNA.
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