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PARN 抗体 (AA 1-280)

This anti-PARN antibody is a 兔 多克隆 antibody detecting PARN in WB 和 IF. Suitable for 人.
产品编号 ABIN6145230
发货至: 中国

Quick Overview for PARN 抗体 (AA 1-280) (ABIN6145230)

抗原

See all PARN 抗体
PARN (Poly A Specific Ribonuclease (PARN))

适用

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宿主

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克隆类型

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多克隆

标记

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This PARN antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-280

    序列

    MEIIRSNFKS NLHKVYQAIE EADFFAIDGE FSGISDGPSV SALTNGFDTP EERYQKLKKH SMDFLLFQFG LCTFKYDYTD SKYITKSFNF YVFPKPFNRS SPDVKFVCQS SSIDFLASQG FDFNKVFRNG IPYLNQEEER QLREQYDEKR SQANGAGALS YVSPNTSKCP VTIPEDQKKF IDQVVEKIED LLQSEENKNL DLEPCTGFQR KLIYQTLSWK YPKGIHVETL ETEKKERYIV ISKVDEEERK RREQQKHAKE QEELNDAVGF SRVIHAIANS

    交叉反应

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PARN (NP_002573.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PARN (Poly A Specific Ribonuclease (PARN))

    别名

    PARN

    背景

    The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PARN,DAN,DKCB6,PFBMFT4,Epigenetics & Nuclear Signaling,RNA Binding,PARN

    分子量

    52 kDa/66 kDa/67 kDa/73 kDa

    基因ID

    5073

    UniProt

    O95453
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