NR1H4 抗体 (AA 207-476)
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北京 101111
Quick Overview for NR1H4 抗体 (AA 207-476) (ABIN6144801)
抗原
See all NR1H4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 207-476
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序列
- CKSKRLRKNV KQHADQTVNE DSEGRDLRQV TSTTKSCREK TELTPDQQTL LHFIMDSYNK QRMPQEITNK ILKEEFSAEE NFLILTEMAT NHVQVLVEFT KKLPGFQTLD HEDQIALLKG SAVEAMFLRS AEIFNKKLPS GHSDLLEERI RNSGISDEYI TPMFSFYKSI GELKMTQEEY ALLTAIVILS PDRQYIKDRE AVEKLQEPLL DVLQKLCKIH QPENPQHFAC LLGRLTELRT FNHHHAEMLM SWRVNDHKFT PLLCEIWDVQ
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 207-476 of human NR1H4 (NP_001193908.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
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别名
- NR1H4
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背景
- This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.,NR1H4,BAR,FXR,HRR-1,HRR1,PFIC5,RIP14,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,NR1H4
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分子量
- 48 kDa/54 kDa/55 kDa
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基因ID
- 9971
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UniProt
- Q96RI1
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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