IL1R1 抗体 (Extracellular Domain)
Quick Overview for IL1R1 抗体 (Extracellular Domain) (ABIN614470)
抗原
See all IL1R1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- These antibodies react with cell surface and soluble human IL-1 receptor. Specific epitopes are unknown, but they do partially inhibit (30-50 %) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for Human IL-2 or IL-4.
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Extracellular domain of the type I Human IL-1 receptor.
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亚型
- IgG2b
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anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 21-109) antibody
IL1R1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 226-318) antibodyIL1R1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 119-217) antibodyIL1R1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 481-569) antibodyIL1R1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 386-553) antibodyIL1R1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 18-167) antibodyIL1R1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4D2D12 unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (pTyr496) antibodyIL1R1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 226-352) antibodyIL1R1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 474-503) antibodyIL1R1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 18-320) antibodyIL1R1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS, pH 7.4
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
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别名
- CD121a / IL1R1
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背景
- IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.Synonyms: IL-1R-alpha, IL1R, IL1RA, IL1RT1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, Interleukin-1 receptor type I
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基因ID
- 3554
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NCBI登录号
- NP_000868
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UniProt
- P14778
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途径
- NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
抗原
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