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NCOR2 抗体 (AA 670-900)

This anti-NCOR2 antibody (ABIN6144422) is a Rabbit Polyclonal antibody detecting NCOR2 in WB, IHC, IF. Suitable for Human.
产品编号 ABIN6144422
发货至: 中国

Quick Overview for NCOR2 抗体 (AA 670-900) (ABIN6144422)

抗原

See all NCOR2 抗体
NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

适用

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宿主

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克隆类型

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多克隆

标记

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This NCOR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 670-900

    序列

    KLKMEKERNA RRKKKKAPAA ASEEAAFPPV VEDEEMEASG VSGNEEEMVE EAEALHASGN EVPRGECSGP ATVNNSSDTE SIPSPHTEAA KDTGQNGPKP PATLGADGPP PGPPTPPPED IPAPTEPTPA SEATGAPTPP PAPPSPSAPP PVVPKEEKEE ETAAAPPVEE GEEQKPPAAE ELAVDTGKAE EPVKSECTEE AEEGPAKGKD AEAAEATAEG ALKAEKKEGG S

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 670-900 of human NCOR2 (NP_006303.4).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

    别名

    NCOR2

    背景

    This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.,NCOR2,CTG26,N-CoR2,SMAP270,SMRT,SMRTE,SMRTE-tau,TNRC14,TRAC,TRAC-1,TRAC1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Notch Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,NCOR2

    分子量

    81 kDa/268 kDa/273 kDa/274 kDa

    基因ID

    9612

    UniProt

    Q9Y618

    途径

    Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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