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MYLK 抗体 (AA 1765-1914)

This anti-MYLK antibody is a 兔 多克隆 antibody detecting MYLK in WB 和 IHC. Suitable for 人.
产品编号 ABIN6144264
发货至: 中国

Quick Overview for MYLK 抗体 (AA 1765-1914) (ABIN6144264)

抗原

See all MYLK 抗体
MYLK (Myosin Light Chain Kinase (MYLK))

适用

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宿主

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克隆类型

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多克隆

标记

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This MYLK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1765-1914

    序列

    SGLSGRKSST GSPTSPLNAE KLESEEDVSQ AFLEAVAEEK PHVKPYFSKT IRDLEVVEGS AARFDCKIEG YPDPEVVWFK DDQSIRESRH FQIDYDEDGN CSLIISDVCG DDDAKYTCKA VNSLGEATCT AELIVETMEE GEGEGEEEEE

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1765-1914 of human MYLK (NP_444253.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MYLK (Myosin Light Chain Kinase (MYLK))

    别名

    MYLK

    背景

    This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.,MYLK,AAT7,KRP,MLCK,MLCK1,MLCK108,MLCK210,MSTP083,MYLK1,s mMLCK,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Actins,MYLK

    分子量

    16 kDa/80 kDa/110 kDa/197-210 kDa

    基因ID

    4638

    UniProt

    Q15746
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