MYLK 抗体 (AA 1765-1914)
Quick Overview for MYLK 抗体 (AA 1765-1914) (ABIN6144264)
抗原
See all MYLK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1765-1914
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序列
- SGLSGRKSST GSPTSPLNAE KLESEEDVSQ AFLEAVAEEK PHVKPYFSKT IRDLEVVEGS AARFDCKIEG YPDPEVVWFK DDQSIRESRH FQIDYDEDGN CSLIISDVCG DDDAKYTCKA VNSLGEATCT AELIVETMEE GEGEGEEEEE
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1765-1914 of human MYLK (NP_444253.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MYLK (Myosin Light Chain Kinase (MYLK))
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别名
- MYLK
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背景
- This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.,MYLK,AAT7,KRP,MLCK,MLCK1,MLCK108,MLCK210,MSTP083,MYLK1,s mMLCK,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Actins,MYLK
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分子量
- 16 kDa/80 kDa/110 kDa/197-210 kDa
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基因ID
- 4638
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UniProt
- Q15746
抗原
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