MYD88 抗体 (AA 60-309)
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北京 101111
Quick Overview for MYD88 抗体 (AA 60-309) (ABIN6144228)
抗原
See all MYD88 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-309
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序列
- WTALAEEMDF EYLEIRQLET QADPTGRLLD AWQGRPGASV GRLLELLTKL GRDDVLLELG PSIEEDCQKY ILKQQQEEAE KPLQVAAVDS SVPRTAELAG ITTLDDPLGH MPERFDAFIC YCPSDIQFVQ EMIRQLEQTN YRLKLCVSDR DVLPGTCVWS IASELIEKRC RRMVVVVSDD YLQSKECDFQ TKFALSLSPG AHQKRLIPIK YKAMKKEFPS ILRFITVCDY TNPCTKSWFW TRLAKALSLP
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交叉反应
- 人, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 60-309 of human MyD88 (NP_002459.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
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别名
- MYD88
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背景
- This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.,MYD88,MYD88D,myeloid differentiation primary response 88,MyD88,Signal Transduction,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,MYD88
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分子量
- 15 kDa/20 kDa/28 kDa/31 kDa/33 kDa/34 kDa
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基因ID
- 4615
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UniProt
- Q99836
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途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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