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MUC1 抗体 (AA 1182-1255)

This anti-MUC1 antibody is a 兔 多克隆 antibody detecting MUC1 in IHC 和 WB. Suitable for 人.
产品编号 ABIN6144194
发货至: 中国

Quick Overview for MUC1 抗体 (AA 1182-1255) (ABIN6144194)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

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    AA 1182-1255

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1182-1255aa of human MUC1 (NP_002708.1).

    亚型

    IgG
  • 应用备注

    WB,1:1000 - 1:3000,IHC,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1

    背景

    This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.,ADMCKD,ADMCKD1,CA 15-3,CD227,EMA,H23AG,KL-6,MAM6,MCD,MCKD,MCKD1,MUC-1,MUC-1/SEC,MUC-1/X,MUC1/ZD,PEM,PEMT,PUM,MUC1,CA15-3,mucin-1,Cancer,Tumor immunology,Tumor-associated antigens,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Immunology & Inflammation,CD markers,MUC1

    分子量

    10-29 kDa/103 kDa/121-122 kDa

    基因ID

    4582

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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