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MCM10 抗体 (AA 616-875)

This anti-MCM10 antibody is a 兔 多克隆 antibody detecting MCM10 in WB. Suitable for 人.
产品编号 ABIN6143639
发货至: 中国

Quick Overview for MCM10 抗体 (AA 616-875) (ABIN6143639)

抗原

See all MCM10 抗体
MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

适用

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宿主

  • 24
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克隆类型

  • 25
多克隆

标记

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This MCM10 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 616-875

    序列

    RLEGAPATMT PKLGRGVLEG DDVLFYDESP PPRPKLSALA EAKKLAAITK LRAKGQVLTK TNPNSIKKKQ KDPQDILEVK ERVEKNTMFS SQAEDELEPA RKKRREQLAY LESEEFQKIL KAKSKHTGIL KEAEAEMQER YFEPLVKKEQ MEEKMRNIRE VKCRVVTCKT CAYTHFKLLE TCVSEQHEYH WHDGVKRFFK CPCGNRSISL DRLPNKHCSN CGLYKWERDG MLKEKTGPKI GGETLLPRGE EHAKFLNSLK

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 616-875 of human MCM10 (NP_877428.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

    别名

    MCM10

    背景

    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.,MCM10,CNA43,DNA43,PRO2249,Epigenetics & Nuclear Signaling,MCM10

    分子量

    98 kDa

    基因ID

    55388

    UniProt

    Q7L590

    途径

    Mitotic G1-G1/S Phases, DNA Replication
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