电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

KPNB1 抗体 (AA 250-350)

This anti-KPNB1 antibody is a 兔 多克隆 antibody detecting KPNB1 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN6142997
发货至: 中国

Quick Overview for KPNB1 抗体 (AA 250-350) (ABIN6142997)

抗原

See all KPNB1 抗体
KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

适用

  • 51
  • 20
  • 19
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 46
  • 4
  • 1
  • 1

克隆类型

  • 47
  • 5
多克隆

标记

  • 28
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KPNB1 antibody is un-conjugated

应用范围

  • 40
  • 15
  • 13
  • 13
  • 12
  • 9
  • 6
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 250-350

    序列

    QYMETYMGPA LFAITIEAMK SDIDEVALQG IEFWSNVCDE EMDLAIEASE AAEQGRPPEH TSKFYAKGAL QYLVPILTQT LTKQDENDDD DDWNPCKAAG V

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 250-350 of human KPNB1 (NP_002256.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

    别名

    KPNB1

    背景

    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene.,KPNB1,IMB1,IPO1,IPOB,Impnb,NTF97,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,KPNB1

    分子量

    81 kDa/97 kDa

    基因ID

    3837

    UniProt

    Q14974

    途径

    Protein targeting to Nucleus
You are here:
Chat with us!