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VEGFR2/CD309 抗体 (AA 1150-1250)

Cited in 1 publication. This 兔 多克隆 anti-VEGFR2/CD309 antibody specifically detects VEGFR2/CD309 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN6142817
发货至: 中国
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Quick Overview for VEGFR2/CD309 抗体 (AA 1150-1250) (ABIN6142817)

抗原

See all VEGFR2/CD309 (VEGFR2) 抗体
VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

适用

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宿主

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克隆类型

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多克隆

标记

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This VEGFR2/CD309 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 1150-1250

    序列

    RPTFSELVEH LGNLLQANAQ QDGKDYIVLP ISETLSMEED SGLSLPTSPV SCMEEEEVCD PKFHYDNTAG ISQYLQNSKR KSRPVSVKTF EDIPLEEPEV K

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1150-1250 of human VEGF Receptor 2 (NP_002244.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Yuan, Shan, Tan, Deng, Liu, Wang, Luo, He, Luo, Zhang, Baker, Olson, Qi: "SRC-3 Plays a Critical Role in Human Umbilical Vein Endothelial Cells by Regulating the PI3K/Akt/mTOR Pathway in Preeclampsia." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 25, Issue 5, pp. 748-758, (2018) (PubMed).

  • 抗原

    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

    别名

    KDR

    背景

    Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.,CD309,FLK1,VEGFR,VEGFR2,VEGF Receptor 2,KDR,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,VEGF,VEGF Receptors,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,Angiogenic growth factors,Hypoxia,KDR

    分子量

    75 kDa/79 kDa/151 kDa

    基因ID

    3791

    UniProt

    P35968

    途径

    RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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