JAK3 抗体 (AA 750-850)
Quick Overview for JAK3 抗体 (AA 750-850) (ABIN6142642)
抗原
See all JAK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 750-850
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序列
- TELALLIQQC MAYEPVQRPS FRAVIRDLNS LISSDYELLS DPTPGALAPR DGLWNGAQLY ACQDPTIFEE RHLKYISQLG KGNFGSVELC RYDPLGDNTG A
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 750-850 of human JAK3 (NP_000206.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- JAK3 (Janus Kinase 3 (JAK3))
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别名
- Jak3
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背景
- The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).,JAK3,JAK-3,JAK3_HUMAN,JAKL,L-JAK,LJAK,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Jak3
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分子量
- 68 kDa/121 kDa/125 kDa
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基因ID
- 3718
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UniProt
- P52333
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
抗原
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