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IL12RB2 抗体 (AA 420-620)

This anti-IL12RB2 antibody is a 兔 多克隆 antibody detecting IL12RB2 in WB. Suitable for 人.
产品编号 ABIN6142303
发货至: 中国

Quick Overview for IL12RB2 抗体 (AA 420-620) (ABIN6142303)

抗原

See all IL12RB2 抗体
IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL12RB2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 420-620

    序列

    GLLAPRQVSA NSEGMDNILV TWQPPRKDPS AVQEYVVEWR ELHPGGDTQV PLNWLRSRPY NVSALISENI KSYICYEIRV YALSGDQGGC SSILGNSKHK APLSGPHINA ITEEKGSILI SWNSIPVQEQ MGCLLHYRIY WKERDSNSQP QLCEIPYRVS QNSHPINSLQ PRVTYVLWMT ALTAAGESSH GNEREFCLQG K

    交叉反应

    小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 420-620 of human IL12RB2 (NP_001550.1).

    亚型

    IgG
  • 应用备注

    WB,1:1000 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

    别名

    IL12RB2

    背景

    The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.,IL12RB2,Cancer,Tumor immunology,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL12RB2

    分子量

    74 kDa/87 kDa/97 kDa

    基因ID

    3595

    UniProt

    Q99665

    途径

    JAK/STAT Signaling
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