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IGF2R 抗体 (AA 2327-2491)

This anti-IGF2R antibody is a 兔 多克隆 antibody detecting IGF2R in WB 和 IF. Suitable for 人.
产品编号 ABIN6142247
发货至: 中国

Quick Overview for IGF2R 抗体 (AA 2327-2491) (ABIN6142247)

抗原

See all IGF2R 抗体
IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

适用

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宿主

  • 64
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克隆类型

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多克隆

标记

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This IGF2R antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 2327-2491

    序列

    YKKERRETVI SKLTTCCRRS SNVSYKYSKV NKEEETDENE TEWLMEEIQL PPPRQGKEGQ ENGHITTKSV KALSSLHGDD QDSEDEVLTI PEVKVHSGRG AGAESSHPVR NAQSNALQER EDDRVGLVRG EKARKGKSSS AQQKTVSSTK LVSFHDDSDE DLLHI

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 2327-2491 of human Cation-independent M6PR (Cation-independent M6PR (IGF2R)) (NP_000867.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

    别名

    IGF2R

    背景

    This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).,IGF2R,CD222,CI-M6PR,CIMPR,M6P-R,M6P/IGF2R,MPR 300,MPR1,MPR300,MPRI,Signal Transduction,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,IGF2R

    分子量

    274 kDa

    基因ID

    3482

    UniProt

    P11717
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