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IDH2 抗体 (AA 193-452)

This anti-IDH2 antibody is a 兔 多克隆 antibody detecting IDH2 in WB, IP, IF 和 ChIP. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6142146
发货至: 中国

Quick Overview for IDH2 抗体 (AA 193-452) (ABIN6142146)

抗原

See all IDH2 抗体
IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

适用

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宿主

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克隆类型

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多克隆

标记

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This IDH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
  • 抗原表位

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    AA 193-452

    序列

    KMVFTPKDGS GVKEWEVYNF PAGGVGMGMY NTDESISGFA HSCFQYAIQK KWPLYMSTKN TILKAYDGRF KDIFQEIFDK HYKTDFDKNK IWYEHRLIDD MVAQVLKSSG GFVWACKNYD GDVQSDILAQ GFGSLGLMTS VLVCPDGKTI EAEAAHGTVT RHYREHQKGR PTSTNPIASI FAWTRGLEHR GKLDGNQDLI RFAQMLEKVC VETVESGAMT KDLAGCIHGL SNVKLNEHFL NTTDFLDTIK SNLDRALGRQ

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 193-452 of human IDH2 (NP_002159.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:20 - 1:50,IP,1:50 - 1:200,ChIP,1:20 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Liang, Lian, Liu, Zhao, Xuan, Guo, Liu, Yang, Dong, Liu, Liu, Zhang: "Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." in: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).

  • 抗原

    IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

    别名

    IDH2

    背景

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.,IDH2,D2HGA2,ICD-M,IDH,IDHM,IDP,IDPM,mNADP-IDH,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,IDH2

    分子量

    45 kDa/50 kDa

    基因ID

    3418

    UniProt

    P48735

    途径

    Warburg Effect
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