ICOSLG 抗体 (AA 19-256)
Quick Overview for ICOSLG 抗体 (AA 19-256) (ABIN6142131)
抗原
See all ICOSLG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-256
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序列
- DTQEKEVRAM VGSDVELSCA CPEGSRFDLN DVYVYWQTSE SKTVVTYHIP QNSSLENVDS RYRNRALMSP AGMLRGDFSL RLFNVTPQDE QKFHCLVLSQ SLGFQEVLSV EVTLHVAANF SVPVVSAPHS PSQDELTFTC TSINGYPRPN VYWINKTDNS LLDQALQNDT VFLNMRGLYD VVSVLRIART PSVNIGCCIE NVLLQQNLTV GSQTGNDIGE RDKITENPVS TGEKNAAT
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 19-256 of human ICOSL (NP_056074.1).
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亚型
- IgG
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anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 23-249) antibody
ICOSLG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 23-149) antibodyICOSLG 适用: 人 WB, ELISA, IHC, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal ICOSL-3111 unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-256) antibodyICOSLG 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1G6E1 unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 58-249) antibodyICOSLG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 197-246) antibodyICOSLG 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 23-149) antibodyICOSLG 适用: 人 ELISA, IHC, Coat, StM, ISt 宿主: 小鼠 Monoclonal ICOSL-3260 unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-120) antibodyICOSLG 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-256) antibodyICOSLG 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 20-302) antibodyICOSLG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) antibodyICOSLG 适用: 小鼠 FACS, BR 宿主: 兔 Chimeric HK5-3 unconjugated Recombinant Antibody
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
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别名
- ICOSLG
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背景
- Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains, and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. Present study shows that ICOSL displays a marked oligomerization potential, resembling more like B7-1 than B7-2. B7-H2-dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. The CD28/B7 and ICOS/B7-H2 pathways are both critical for costimulating T cell immune responses. Deficiency in either pathway results in defective T cell activation, cytokine production and germinal center formation.,ICOSLG,B7-H2,B7H2,B7RP-1,B7RP1,CD275,GL50,ICOS-L,ICOSL,LICOS,Immunology & Inflammation,CD markers,ICOSLG
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分子量
- 20 kDa/33 kDa/34 kDa
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基因ID
- 23308
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UniProt
- O75144
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途径
- Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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