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HLA-DRA 抗体 (AA 26-216)

This anti-HLA-DRA antibody is a 兔 多克隆 antibody detecting HLA-DRA in WB 和 IHC. Suitable for 人.
产品编号 ABIN6141827
发货至: 中国

Quick Overview for HLA-DRA 抗体 (AA 26-216) (ABIN6141827)

抗原

See all HLA-DRA 抗体
HLA-DRA (HLA Class II DR alpha (HLA-DRA))

适用

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宿主

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克隆类型

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多克隆

标记

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This HLA-DRA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 26-216

    序列

    IKEEHVIIQA EFYLNPDQSG EFMFDFDGDE IFHVDMAKKE TVWRLEEFGR FASFEAQGAL ANIAVDKANL EIMTKRSNYT PITNVPPEVT VLTNSPVELR EPNVLICFID KFTPPVVNVT WLRNGKPVTT GVSETVFLPR EDHLFRKFHY LPFLPSTEDV YDCRVEHWGL DEPLLKHWEF DAPSPLPETT E

    交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human HLA-DRA (NP_061984.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    HLA-DRA (HLA Class II DR alpha (HLA-DRA))

    别名

    HLA-DRA

    背景

    HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.,HLA-DRA,HLA-DRA1,major histocompatibility complex,class II,DR alpha,Immunology & Inflammation,HLA-DRA

    分子量

    28 kDa

    基因ID

    3122

    UniProt

    P01903

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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