HECTD1 抗体 (AA 2518-2610)
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北京 101111
Quick Overview for HECTD1 抗体 (AA 2518-2610) (ABIN6141706)
抗原
See all HECTD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2518-2610
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序列
- PGFLRFVRVL CGMSSDERKA FLQFTTGCST LPPGGLANLH PRLTVVRKVD ATDASYPSVN TCVHYLKLPE YSSEEIMRER LLAATMEKGF HLN
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 2518-2610 of human HECTD1 (NP_056197.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- HECTD1 (HECT Domain Containing 1 (HECTD1))
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别名
- HECTD1
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背景
- E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.,HECTD1,EULIR,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,HECTD1
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分子量
- 289 kDa
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基因ID
- 25831
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UniProt
- Q9ULT8
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途径
- Tube Formation, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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