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HECTD1 抗体

HECTD1 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074186
发货至: 中国
  • 抗原 See all HECTD1 抗体
    HECTD1 (HECT Domain Containing 1 (HECTD1))
    适用
    • 30
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    大鼠
    宿主
    • 25
    • 5
    克隆类型
    • 26
    • 4
    多克隆
    标记
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    • 1
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    This HECTD1 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 2
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse HECTD1
  • 应用备注
    IHC/IF (R) 1:1000-1:2000/1:1000-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    HECTD1 (HECT Domain Containing 1 (HECTD1))
    别名
    HECTD1 (HECTD1 产品)
    别名
    RGD1561653 antibody, HECTD1 antibody, hectd1 antibody, MGC172681 antibody, A630086P08Rik antibody, AI844876 antibody, b2b327Clo antibody, opm antibody, HECT domain E3 ubiquitin protein ligase 1 antibody, HECT domain containing E3 ubiquitin protein ligase 1 antibody, Hectd1 antibody, HECTD1 antibody, hectd1 antibody
    背景
    HECTD1 (E3 ubiquitin-protein ligase, which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates . Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion . Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells impairs their emigration and is consequently essential for the correct development of the cranial neural folds and neural tube closure.It is also involved in sporadic Parkinson's disease.
    UniProt
    Q69ZR2
    途径
    Tube Formation, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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