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FLT1 抗体 (AA 20-300)

This anti-FLT1 antibody is a 兔 多克隆 antibody detecting FLT1 in WB 和 IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6140687
发货至: 中国

Quick Overview for FLT1 抗体 (AA 20-300) (ABIN6140687)

抗原

See all FLT1 抗体
FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

适用

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宿主

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克隆类型

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  • 56
多克隆

标记

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This FLT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 20-300

    序列

    LTGSSSGSKL KDPELSLKGT QHIMQAGQTL HLQCRGEAAH KWSLPEMVSK ESERLSITKS ACGRNGKQFC STLTLNTAQA NHTGFYSCKY LAVPTSKKKE TESAIYIFIS DTGRPFVEMY SEIPEIIHMT EGRELVIPCR VTSPNITVTL KKFPLDTLIP DGKRIIWDSR KGFIISNATY KEIGLLTCEA TVNGHLYKTN YLTHRQTNTI IDVQISTPRP VKLLRGHTLV LNCTATTPLN TRVQMTWSYP DEKNKRASVR RRIDQSNSHA NIFYSVLTID K

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human VEGFR1 (NP_001153392.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Huang, Rehman, Lan, Qiu, Zhang, Iqbal, Luo, Mehmood, Zhang, Li: "Tibial dyschondroplasia is highly associated with suppression of tibial angiogenesis through regulating the HIF-1α/VEGF/VEGFR signaling pathway in chickens." in: Scientific reports, Vol. 7, Issue 1, pp. 9089, (2017) (PubMed).

  • 抗原

    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

    别名

    FLT1

    背景

    This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.,FLT,FLT-1,VEGFR-1,VEGFR1,FLT1,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,VEGF,VEGF Receptors,Endocrine & Metabolism,Cardiovascular,Angiogenesis,Angiogenic growth factors,Hypoxia,FLT1

    分子量

    39 kDa/41 kDa/52- 82 kDa/150 kDa

    基因ID

    2321

    UniProt

    P17948

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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