FADD 抗体 (AA 1-208)
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北京 101111
Quick Overview for FADD 抗体 (AA 1-208) (ABIN6140432)
抗原
See all FADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-208
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序列
- MDPFLVLLHS VSSSLSSSEL TELKFLCLGR VGKRKLERVQ SGLDLFSMLL EQNDLEPGHT ELLRELLASL RRHDLLRRVD DFEAGAAAGA APGEEDLCAA FNVICDNVGK DWRRLARQLK VSDTKIDSIE DRYPRNLTER VRESLRIWKN TEKENATVAH LVGALRSCQM NLVADLVQEV QQARDLQNRS GAMSPMSWNS DASTSEAS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human FADD (NP_003815.1).
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亚型
- IgG
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anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 12-206) antibody
FADD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 20-150) antibodyFADD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5A6A2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 7-178) antibodyFADD 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibodyFADD 适用: 小鼠 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal J1D2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 109-208) antibodyFADD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-80) antibodyFADD 适用: 人, 小鼠, 大鼠, 猴, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibodyFADD 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3590 unconjugated Recombinant Antibody
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (pSer191) antibodyFADD 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 7333, (2017) (PubMed).
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: "D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 7333, (2017) (PubMed).
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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别名
- FADD
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背景
- The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.,GIG3,MORT1,FADD,FADD,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Death receptors & ligands,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,FADD
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分子量
- 23 kDa
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基因ID
- 8772
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UniProt
- Q13158
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途径
- Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
抗原
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