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EZH2 抗体 (AA 1-250)

This anti-EZH2 antibody is a 兔 多克隆 antibody detecting EZH2 in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6140393
发货至: 中国

Quick Overview for EZH2 抗体 (AA 1-250) (ABIN6140393)

抗原

See all EZH2 抗体
EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

适用

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宿主

  • 90
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  • 1

克隆类型

  • 76
  • 47
多克隆

标记

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This EZH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-250

    序列

    MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL ERTEILNQEW KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT LNAVASVPIM YSWSPLQQNF MVEDETVLHN IPYMGDEVLD QDGTFIEELI KNYDGKVHGD RECGFINDEI FVELVNALGQ YNDDDDDDDG DDPEEREEKQ KDLEDHRDDK ESRPPRKFPS DKIFEAISSM FPDKGTAEEL KEKYKELTEQ

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EZH2/KMT6 (NP_001190176.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Cao, Liu, Yue, Liu, Pei, Gu, Wang, Jia: "Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer." in: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 31, Issue 5, pp. 797-805, (2018) (PubMed).

  • 抗原

    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

    别名

    EZH2

    背景

    This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.,ENX-1,ENX1,EZH1,EZH2b,KMT6,KMT6A,WVS,WVS2,EZH2,KMT6 / EZH2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Chromatin Remodeling,Cancer,Tumor biomarkers,EZH2

    分子量

    79 kDa/81 kDa/84 kDa/85 kDa/86 kDa

    基因ID

    2146

    UniProt

    Q15910

    途径

    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
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