EZH2 抗体 (AA 1-250)
Quick Overview for EZH2 抗体 (AA 1-250) (ABIN6140393)
抗原
See all EZH2 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 1-250
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                                            序列
- MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL ERTEILNQEW KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT LNAVASVPIM YSWSPLQQNF MVEDETVLHN IPYMGDEVLD QDGTFIEELI KNYDGKVHGD RECGFINDEI FVELVNALGQ YNDDDDDDDG DDPEEREEKQ KDLEDHRDDK ESRPPRKFPS DKIFEAISSM FPDKGTAEEL KEKYKELTEQ
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            产品特性
- Polyclonal Antibodies
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                                            纯化方法
- Affinity purification
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                                            免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EZH2/KMT6 (NP_001190176.1).
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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                                            说明
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                        HIGH QUALITY 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - 
                                            : "Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer."    in: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 31, Issue 5, pp. 797-805, (2018)         (PubMed).        
 
 
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                                            : "Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer."    in: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 31, Issue 5, pp. 797-805, (2018)         (PubMed).        
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    - EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
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                                            别名
- EZH2
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                                            背景
- This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.,ENX-1,ENX1,EZH1,EZH2b,KMT6,KMT6A,WVS,WVS2,EZH2,KMT6 / EZH2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Chromatin Remodeling,Cancer,Tumor biomarkers,EZH2
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                                            分子量
- 79 kDa/81 kDa/84 kDa/85 kDa/86 kDa
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                                            基因ID
- 2146
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                                            UniProt
- Q15910
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                                            途径
- Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
 抗原
- 
                    
 
                                     
                                     
                                    