p300 抗体 (AA 1-270)
Quick Overview for p300 抗体 (AA 1-270) (ABIN6140193)
抗原
See all p300 (EP300) 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            抗原表位
- AA 1-270
- 
                                            序列
- MAENVVEPGP PSAKRPKLSS PALSASASDG TDFGSLFDLE HDLPDELINS TELGLTNGGD INQLQTSLGM VQDAASKHKQ LSELLRSGSS PNLNMGVGGP GQVMASQAQQ SSPGLGLINS MVKSPMTQAG LTSPNMGMGT SGPNQGPTQS TGMMNSPVNQ PAMGMNTGMN AGMNPGMLAA GNGQGIMPNQ VMNGSIGAGR GRQNMQYPNP GMGSAGNLLT EPLQQGSPQM GGQTGLRGPQ PLKMGMMNNP NPYGSPYTQN PGQQIGASGL
- 
                                            交叉反应
- 人, 小鼠, 大鼠
- 
                                            产品特性
- Polyclonal Antibodies
- 
                                            纯化方法
- Affinity purification
- 
                                            免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human EP300 (NP_001420.2).
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Liquid
- 
                                            缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
- 
                                            
- 
    - 
                                            : "Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway."    in: Archives of biochemistry and biophysics, Vol. 640, pp. 37-46, (2018)         (PubMed).        
 
 
- 
                                            : "Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway."    in: Archives of biochemistry and biophysics, Vol. 640, pp. 37-46, (2018)         (PubMed).        
- 
    - p300 (EP300) (E1A Binding Protein P300 (EP300))
- 
                                            别名
- EP300
- 
                                            背景
- This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.,EP300,KAT3B,RSTS2,p300,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,Transcription Factors,Nuclear Receptor Signaling,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,G2/M DNA Damage Checkpoint,Notch Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,NF-kB Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Stem Cells,Cardiovascular,Angiogenesis,EP300
- 
                                            分子量
- 264 kDa
- 
                                            基因ID
- 2033
- 
                                            UniProt
- Q09472
- 
                                            途径
- p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
 抗原
- 
                    
 
                                     
                                     
                                    