Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) 抗体
Quick Overview for Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) 抗体 (ABIN6139873)
抗原
See all Dual Specificity Phosphatase 3 (DUSP3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-185
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序列
- MSGSFELSVQ DLNDLLSDGS GCYSLPSQPC NEVTPRIYVG NASVAQDIPK LQKLGITHVL NAAEGRSFMH VNTNANFYKD SGITYLGIKA NDTQEFNLSA YFERAADFID QALAQKNGRV LVHCREGYSR SPTLVIAYLM MRQKMDVKSA LSIVRQNREI GPNDGFLAQL CQLNDRLAKE GKLKP
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human DUSP3 (NP_004081.1).
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亚型
- IgG
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anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) antibody
DUSP3 适用: 人 WB 宿主: 小鼠 Monoclonal 2# unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) antibodyDUSP3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) antibodyDUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 1-30), (N-Term) antibodyDUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06032 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) antibodyDUSP3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (C-Term) antibodyDUSP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (N-Term) antibodyDUSP3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 157-185), (C-Term) antibodyDUSP3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB5730 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (C-Term) antibodyDUSP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 14-96) antibodyDUSP3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Dual Specificity Phosphatase 3 (DUSP3)
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别名
- DUSP3
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背景
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.,DUSP3,VHR,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,DUSP3
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分子量
- 16 kDa/20 kDa
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基因ID
- 1845
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UniProt
- P51452
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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