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CTLA4 抗体 (AA 49-223)

This anti-CTLA4 antibody is a 兔 多克隆 antibody detecting CTLA4 in WB. Suitable for 人.
产品编号 ABIN6139198
发货至: 中国

Quick Overview for CTLA4 抗体 (AA 49-223) (ABIN6139198)

抗原

See all CTLA4 抗体
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

适用

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宿主

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克隆类型

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多克隆

标记

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This CTLA4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 49-223

    序列

    SSRGIASFVC EYASPGKATE VRVTVLRQAD SQVTEVCAAT YMMGNELTFL DDSICTGTSS GNQVNLTIQG LRAMDTGLYI CKVELMYPPP YYLGIGNGTQ IYVIDPEPCP DSDFLLWILA AVSSGLFFYS FLLTAVSLSK MLKKRSPLTT GVYVKMPPTE PECEKQFQPY FIPIN

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 49-223 of human CTLA4 (NP_005205.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    别名

    CTLA4

    背景

    This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.,CTLA4,ALPS5,CD,CD152,CELIAC3,CTLA-4,GRD4,GSE,IDDM12,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CTLA4

    分子量

    6 kDa/8 kDa/19 kDa/24 kDa

    基因ID

    1493

    UniProt

    P16410

    途径

    Cancer Immune Checkpoints
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