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CFHR5 抗体 (AA 450-569)

This anti-CFHR5 antibody is a 兔 多克隆 antibody detecting CFHR5 in WB. Suitable for 人.
产品编号 ABIN6138459
发货至: 中国

Quick Overview for CFHR5 抗体 (AA 450-569) (ABIN6138459)

抗原

See all CFHR5 抗体
CFHR5 (Complement Factor H-Related 5 (CFHR5))

适用

  • 35
  • 10

宿主

  • 22
  • 13

克隆类型

  • 23
  • 12
多克隆

标记

  • 20
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CFHR5 antibody is un-conjugated

应用范围

  • 24
  • 15
  • 15
  • 11
  • 5
  • 5
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 450-569

    序列

    GPPPSINNGD TTSFPLSVYP PGSTVTYRCQ SFYKLQGSVT VTCRNKQWSE PPRCLDPCVV SEENMNKNNI QLKWRNDGKL YAKTGDAVEF QCKFPHKAMI SSPPFRAICQ EGKFEYPICE

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 450-569 of human CFHR5 (NP_110414.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CFHR5 (Complement Factor H-Related 5 (CFHR5))

    别名

    CFHR5

    背景

    This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).,CFHR5,CFHL5,CFHR5D,FHR-5,FHR5,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFHR5

    分子量

    64 kDa

    基因ID

    81494

    UniProt

    Q9BXR6
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