Survivin 抗体 (AA 1-142)
Quick Overview for Survivin 抗体 (AA 1-142) (ABIN6137562)
抗原
See all Survivin (BIRC5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-142
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序列
- MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE FLKLDRERAK NKIAKETNNK KKEFEETAEK VRRAIEQLAA MD
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human Survivin (NP_001159.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease." in: Experimental neurology, Vol. 297, pp. 36-49, (2017) (PubMed).
: "GLP1 protects cardiomyocytes from palmitate-induced apoptosis via Akt/GSK3b/b-catenin pathway." in: Journal of molecular endocrinology, Vol. 55, Issue 3, pp. 245-62, (2016) (PubMed).
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: "Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease." in: Experimental neurology, Vol. 297, pp. 36-49, (2017) (PubMed).
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- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
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别名
- BIRC5
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背景
- This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,API4,EPR-1,BIRC5,Survivin,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Death receptors & ligands,Cell Cycle,Centrosome,Centromere,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Astrocyte marker,BIRC5
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分子量
- 8 kDa/13 kDa/15 kDa/16 kDa/18 kDa
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基因ID
- 332
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UniProt
- O15392
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途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
抗原
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