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MAPK14 抗体 (pThr180, pTyr182)

This anti-MAPK14 antibody is a 兔 多克隆 antibody detecting MAPK14 in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6136138
发货至: 中国

Quick Overview for MAPK14 抗体 (pThr180, pTyr182) (ABIN6136138)

抗原

See all MAPK14 抗体
MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

适用

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宿主

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克隆类型

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多克隆

标记

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This MAPK14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    pThr180, pTyr182

    序列

    MTGYV

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    免疫原

    A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK (NP_620581.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Yuan, Zhu, Hong, Sun, Fang, Wu, Li: "The role of cPLA2 in Methylglyoxal-induced cell apoptosis of HUVECs." in: Toxicology and applied pharmacology, Vol. 323, pp. 44-52, (2017) (PubMed).

  • 抗原

    MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

    别名

    MAPK14

    背景

    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,MAPK14,CSBP,CSBP1,CSBP2,CSPB1,EXIP,Mxi2,PRKM14,PRKM15,RK,SAPK2A,p38,p38ALPHA,p38 MAPK,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,Kinase,Serine/threonine kinases,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,Protein phosphorylation,MAPK14

    分子量

    29 kDa/34 kDa/35 kDa/41 kDa

    基因ID

    5600, 6300, 5603

    UniProt

    Q15759, P53778, O15264, Q16539

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
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