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beta Arrestin 1 抗体

This anti-beta Arrestin 1 antibody is a 兔 单克隆 antibody detecting beta Arrestin 1 in WB. Suitable for 人.
产品编号 ABIN6135523
发货至: 中国

Quick Overview for beta Arrestin 1 抗体 (ABIN6135523)

抗原

See all beta Arrestin 1 (ARRB1) 抗体
beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

适用

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宿主

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克隆类型

  • 75
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单克隆

标记

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This beta Arrestin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    人, 小鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human beta-arrestin1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

    别名

    ARRB1

    背景

    Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.,ARRB1,ARB1,ARR1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),G2/M DNA Damage Checkpoint,Kinase,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Notch Signaling Pathway,Neuroscience,Neurodegenerative Diseases,ARRB1

    分子量

    46 kDa/47 kDa

    基因ID

    408

    UniProt

    P49407

    途径

    Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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