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CD70 抗体 (PE)

Cited in 2+ publications. This PE-conjugated 小鼠 单克隆 anti-CD70 antibody (Clone BU69) specifically detects CD70 in ELISA, FACS, IHC, IHC (fro), ICC 和 Func. The antibody is reactive with 人 samples.
产品编号 ABIN610197
发货至: 中国
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Quick Overview for CD70 抗体 (PE) (ABIN610197)

抗原

See all CD70 抗体
CD70 (CD70 Molecule (CD70))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD70 antibody is conjugated to PE

应用范围

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ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Functional Studies (Func)

克隆位点

BU69
  • 特异性

    CD70 Molecule of approximately 30 kd.

    纯化方法

    Gel filtration

    免疫原

    Human WM-1 (Waldenstrpm's macroglobulinemia) cell line.

    亚型

    IgG1
  • 应用备注

    Approved: ELISA, Flo, Func, ICC, IHC, IHC-Fr

    Usage: Function: Blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells. One test is 1.6 μL per 5 x 10e5 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze. Product is photosensitive and should be protected from light.

    储存条件

    4 °C

    储存方法

    Store at 4°C. Do not freeze. Protect from light.
  • MacLaren, Clark, Gillespie: "v-Jun sensitizes cells to apoptosis by a mechanism involving mitochondrial cytochrome C release." in: Oncogene, Vol. 19, Issue 51, pp. 5906-18, (2000) (PubMed).

    Arnold, Seifert, Asadullah, Volk: "Crosstalk between keratinocytes and T lymphocytes via Fas/Fas ligand interaction: modulation by cytokines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 12, pp. 7140-7, (1999) (PubMed).

  • 抗原

    CD70 (CD70 Molecule (CD70))

    别名

    CD70

    背景

    Name/Gene ID: CD70
    Family: TNF

    Synonyms: CD70, CD27LG, Ki-24 antigen, Surface antigen CD70, CD27 ligand, CD27-L, CD70 antigen, CD70 Molecule, TNFSF7

    基因ID

    970

    UniProt

    P32970

    途径

    Cancer Immune Checkpoints
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