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CD70 抗体

Cited in 2+ publications. This anti-CD70 antibody is a 小鼠 单克隆 antibody detecting CD70 in ELISA, FACS, IHC, IHC (fro), ICC 和 Func. Suitable for 人.
产品编号 ABIN610194
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD70 抗体 (ABIN610194)

抗原

See all CD70 抗体
CD70 (CD70 Molecule (CD70))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD70 antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Functional Studies (Func)

克隆位点

BU69
  • 特异性

    CD70 Molecule of approximately 30 kd.

    纯化方法

    Protein A purified

    免疫原

    Human WM-1 (Waldenstrpm's macroglobulinemia) cell line.

    亚型

    IgG1
  • 应用备注

    Approved: ELISA, Flo, Func, ICC, IHC, IHC-Fr

    Usage: Function: Blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/mL Gentamicin sulfate

    储存液

    Gentamicin sulfate

    注意事项

    This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 4°C. Do not freeze.
  • Baki, Marambaud, Efthimiopoulos, Georgakopoulos, Wen, Cui, Shioi, Koo, Ozawa, Friedrich, Robakis: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).

    Huan, van Adelsberg: "Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins." in: The Journal of clinical investigation, Vol. 104, Issue 10, pp. 1459-68, (1999) (PubMed).

  • 抗原

    CD70 (CD70 Molecule (CD70))

    别名

    CD70

    背景

    Name/Gene ID: CD70
    Family: TNF

    Synonyms: CD70, CD27LG, Ki-24 antigen, Surface antigen CD70, CD27 ligand, CD27-L, CD70 antigen, CD70 Molecule, TNFSF7

    基因ID

    970

    UniProt

    P32970

    途径

    Cancer Immune Checkpoints
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