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ERK1/2 抗体 (Tyr204)

This anti-ERK1/2 antibody is a 兔 多克隆 antibody detecting ERK1/2 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5960944
发货至: 中国

Quick Overview for ERK1/2 抗体 (Tyr204) (ABIN5960944)

抗原

See all ERK1/2 (MAPK1/3) 抗体
ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

适用

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人, 小鼠, 大鼠

宿主

  • 139
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克隆类型

  • 133
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多克隆

标记

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This ERK1/2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Tyr204

    特异性

    MAPK3,ERK1,PRKM3,Mitogen-activated protein kinase 3,MAP kinase 3,MAPK 3,ERT2,Extracellular signal-regulated kinase 1,ERK-1,Insulin-stimulated MAP2 kinase,MAP kinase isoform p44,p44-MAPK,Microtubule-associated protein 2 kinase,p

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human ERK 1/2 around the non-phosphorylation site of Tyr204.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

    别名

    ERK 1/2

    背景

    Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1, required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.

    分子量

    43kDa

    基因ID

    5595, 5594
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