SIRT1 抗体 (Ser47)
Quick Overview for SIRT1 抗体 (Ser47) (ABIN5958340)
抗原
See all SIRT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser47
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特异性
- 75SirT1,hSIR2,hSIRT1,HST2,S. cerevisiae,homolog of,NAD dependent deacetylase sirtuin 1,NAD dependent protein deacetylase sirtuin 1,OTTHUMP00000198111,OTTHUMP00000198112,Regulatory protein SIR2 homolog 1,SIR1,SIR2,SIR2 like 1,SIR2 like protein 1,SIR2,S.cerevisiae,homolog-like 1,SIR2-like protein 1,SIR2ALPHA,SIR2L1,Sirt1,SirtT1 75 kDa fragment,Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae),Sirtuin 1,Sirtuin type 1
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human SIRT1 around the non-phosphorylation site of Ser47.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SIRT1 (Sirtuin 1 (SIRT1))
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别名
- SIRT1
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背景
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins witHuman, Mouseono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
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分子量
- 82kDa
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基因ID
- 23411
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UniProt
- Q96EB6
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途径
- MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
抗原
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