SMAD2 抗体 (Ser467)
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北京 101111
Quick Overview for SMAD2 抗体 (Ser467) (ABIN5957447)
抗原
See all SMAD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser467
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特异性
- Drosophila,homolog of,MADR2,hMAD-2,HsMAD2,JV18,JV18-1,JV181,MAD,MAD homolog 2,MAD Related Protein 2,Mad-related protein 2,MADH2,MADR2,MGC22139,MGC34440,Mother against DPP homolog 2,Mothers against decapentaplegic homolog 2,Mothers against decapentaplegic,Drosophila,homolog of,2,Mothers against DPP homolog 2,OTTHUMP00000163489,Sma and Mad related protein 2,Sma- and Mad-related protein 2 MAD,SMAD 2,SMAD family member 2,SMAD,mothers against DPP homolog 2,SMAD2,SMAD2
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human Smad2 around the non-phosphorylation site of Ser467.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
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别名
- Smad2
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背景
- Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.
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分子量
- 52kDa
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基因ID
- 4087
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UniProt
- Q15796
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途径
- Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
抗原
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