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EGFR 抗体 (Tyr1172)

Name: EGFR 抗体 (Tyr1172)
SKU: ABIN5956472
Availability: OutOfStock

This 兔多克隆 antibody specifically detects EGFR in WB, ELISA 和 IHC (p). It exhibits reactivity toward 人, 小鼠和大鼠.

Western Blotting (WB) image for anti-Epidermal Growth Factor Receptor (EGFR) (Tyr1172) antibody (ABIN5956472) (EGFR 抗体 (Tyr1172))

1 image

产品编号 ABIN5956472

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EGFR 抗体 (Tyr1172) (ABIN5956472)

抗原

See all EGFR 抗体

EGFR (Epidermal Growth Factor Receptor (EGFR))

适用

1023
317
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26
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19
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3
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1
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人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This EGFR antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product EGFR Primary Antibody

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Tyr1172

特异性

Avian erythroblastic leukemia viral (v erb b) oncogene homolog,Cell growth inhibiting protein 40,Cell proliferation inducing protein 61,EGF R,EGFR,EGFR,Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog),Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian),Epidermal growth factor receptor,erb-b2 receptor tyrosine kinase 1,ERBB,ERBB1,Errp,HER1,mENA,NISBD2,Oncogen ERBB,PIG61,Proto-oncogene c-ErbB-1,Receptor tyrosine protein kinase ErbB 1,Receptor tyrosine-protein kinase ErbB-1,SA7,Species antigen 7,Urogastrone,v-erb-b Avian erythroblastic leukemia viral oncogen homolog,wa2,Wa5

纯化方法

Affinity purification

免疫原

Synthesized peptide derived from human EGFR around the non-phosphorylation site of Tyr1172.

亚型

IgG
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7A6F12 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibody
EGFR 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C4 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 小鸡, 犬, 马, 兔, 豚鼠, Avian, Cat, 驴, 山羊, Hamster, 绵羊 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5E10D3 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) antibody
KD Validated EGFR 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB4395 unconjugated Recombinant Antibody

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1163-1191), (C-Term) antibody
EGFR 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 688CT33-1-3 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR 适用: 人, 大鼠 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000

限制

仅限研究用
浓度

1 mg/mL

缓冲液

PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
抗原

EGFR (Epidermal Growth Factor Receptor (EGFR))

别名

EGFR

背景

Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin.Isoform 2 may act as an antagonist of EGF action.

分子量

134kDa

基因ID

1956

UniProt

P00533

途径

NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins