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PRKAA1/PRKAA2 抗体 (Thr172, Thr183)

This 兔 多克隆 antibody specifically detects PRKAA1/PRKAA2 in WB, ELISA 和 IHC (p). It exhibits reactivity toward 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN5956004
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PRKAA1/PRKAA2 抗体 (Thr172, Thr183) (ABIN5956004)

抗原

PRKAA1/PRKAA2 (AMPK1/AMPK2)

适用

  • 43
  • 43
  • 42
  • 19
  • 16
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠, 猴

宿主

  • 43
  • 1

克隆类型

  • 24
  • 20
多克隆

标记

  • 11
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PRKAA1/PRKAA2 antibody is un-conjugated

应用范围

  • 43
  • 23
  • 14
  • 13
  • 13
  • 13
  • 9
  • 7
  • 5
  • 4
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 38
    • 37
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Thr172, Thr183

    特异性

    PRKAA1,AMPK1,5'-AMP-activated protein kinase catalytic subunit alpha-1,AMPK subunit alpha-1,Acetyl-CoA carboxylase kinase,ACACA kinase,Hydroxymethylglutaryl-CoA reductase kinase,HMGCR kinase,Tau-protein kinase PRKAA1,PRKAA2,AMPK,

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human AMPKalpha1/2 around the non-phosphorylation site of Thr183/172.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PRKAA1/PRKAA2 (AMPK1/AMPK2)

    别名

    AMPK alpha1/2

    背景

    AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic α subunit and regulatory β and γ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.

    分子量

    62kDa

    基因ID

    5562, 5563
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