2 methylacyl CoA racemase,2-methylacyl-CoA racemase,Alpha methylacyl CoA racemase,Alpha-methylacyl-CoA racemase,Amacr,AMACR,AMACRD,CBAS4,EC 5.1.99.4,Macr1,RACE,RM
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
AMACR
(alpha-Methylacyl-CoA Racemase (AMACR))
别名
AMACR
背景
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.