TXNRD1 抗体 (AA 161-647)
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Quick Overview for TXNRD1 抗体 (AA 161-647) (ABIN5776265)
抗原
See all TXNRD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 161-647
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原理
- Human Thioredoxin Reductase 1/TRXR1 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human TXNRD1 (161-647aa) purified from E. coli
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亚型
- IgG2b kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
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别名
- Thioredoxin Reductase 1/TRXR1
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背景
- TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
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NCBI登录号
- NP_001087240
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途径
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
抗原
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