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AKT1 抗体 (AA 1-480)
AKT1
适用: 人
WB, ELISA, IF, FACS, ICC
宿主: 小鼠
Monoclonal
AT6D5
unconjugated
AKT1抗体详情
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抗原
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AKT1
(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
抗原表位
All epitopes for AKT1 抗体
AA 1-480
适用
All reactivities for AKT1 抗体
人
宿主
All hosts for AKT1 抗体
小鼠
克隆类型
All clonalities for AKT1 抗体
单克隆
标记
All conjugates for AKT1 抗体
This AKT1 antibody is un-conjugated
应用范围
All applications for AKT1 抗体
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
免疫原
Recombinant human AKT1 (1-480aa) purified from insect cell.
克隆位点
AT6D5
亚型
IgG2a kappa
Top Product
Discover our top product AKT1 Primary Antibody
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使用细节
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仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
储存条件
4 °C,-20 °C,-80 °C
储存方法
Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
AKT1目标详情
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抗原
AKT1
(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
别名
Akt1 (AKT1 产品 )
背景
AKT1, also known as RAC-alpha serine/threonine-protein kinase, is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
NCBI登录号
NP_001014432
途径
PI3K-Akt Signaling , RTK signaling , TCR Signaling , AMPK Signaling , Interferon-gamma Pathway , TLR signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Response to Water Deprivation , Regulation of Actin Filament Polymerization , Carbohydrate Homeostasis , Glycosaminoglycan Metabolic Process , Cellular Glucan Metabolic Process , Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Regulation of Cell Size , Skeletal Muscle Fiber Development , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Protein targeting to Nucleus , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Negative Regulation of intrinsic apoptotic Signaling , Thromboxane A2 Receptor Signaling , Signaling of Hepatocyte Growth Factor Receptor , Positive Regulation of fat Cell Differentiation , VEGFR1 Specific Signals , VEGF Signaling , Warburg Effect
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