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Integrin beta 2 抗体 (PE)

This anti-Integrin beta 2 antibody is a 大鼠 单克隆 antibody detecting Integrin beta 2 in FACS, IHC, IP, IHC (fro) 和 BR. Suitable for 人 和 犬.
产品编号 ABIN576530
发货至: 中国

Quick Overview for Integrin beta 2 抗体 (PE) (ABIN576530)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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人, 犬

宿主

  • 105
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  • 1
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大鼠

克隆类型

  • 135
  • 94
  • 2
单克隆

标记

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This Integrin beta 2 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)
  • 特异性

    YFC118.3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen (code number N221) as recognizing the CD18 antigen. The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The main cellular reactivity of antibody YFC 118.3 is a strong reactivity with Leucocytes (platelets negative). The CD18 Molecule is the receptor for ICAM-1 and is thus important for cell adhesion. YFC118.3 blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.

    纯化方法

    Protein G purified

    免疫原

    Human neutrophils.

    Type of Immunogen: Cells

    亚型

    IgG2b
  • 应用备注

    Approved: Block, Flo (1:1), IHC, IHC-Fr, IP

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL whole blood or 10^6 cells in 100 μL. Method sheets are available on request.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Distilled Water.

    浓度

    Lot specific

    缓冲液

    Lyophilized, PBS,  pH 7.2, 0.09 % sodium azide, 1 % BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    ITGB2 / MAC-1 / CD18

    背景

    Name/Gene ID: ITGB2
    Family: Integrin

    Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

    基因ID

    3689

    UniProt

    P05107

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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