PRKDC 抗体
Quick Overview for PRKDC 抗体 (ABIN576237)
抗原
See all PRKDC 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes the human DNA-dependent protein kinase catalytic subunit, also known as DNA-PKcs, DNPK1 or p460. DNA PKcs is a 4128 amino acid ~460 kD nuclear protein encoded by the PRKDC gene, acting as a molecular sensor for DNA damage. Mutation of the PRKDC gene can result in Immunodeficiency 26 with or without neurologic abnormalities.
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免疫原
- Human DNA-PKcs fragment.
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亚型
- IgG
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应用备注
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Approved: GS, IHC, IHC-P (1:100), IP, WB (1:2000)
Usage: Immunohistology: This product requires heat mediated treatment of paraffin sections. We recommend the use of antigen unmasking fluid for this purpose. A two hour incubation with LS-C42724 is recommended. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Serum, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
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别名
- PRKDC / DNA-PKcs
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背景
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Name/Gene ID: PRKDC
Subfamily: PI3/PI4
Family: Protein Kinase
Synonyms: PRKDC, DNA-PK, DNAPK, DNPK1, HYRC, HYRC1, p350, Scid, XRCC7, DNA-PK catalytic subunit, DNA-PKcs, p460, DNA-dependent protein kinase catalytic subunit -
基因ID
- 5591
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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