Contactin 1 抗体 (AA 100-150)
Quick Overview for Contactin 1 抗体 (AA 100-150) (ABIN571798)
抗原
See all Contactin 1 (CNTN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-150
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原理
- Rabbit antibody to Contactin 1
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特异性
- Specific for contactin-1.
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交叉反应
- 人, 大鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from AA 100-150 of human contactin 1 conjugated to an immunogenic carrier protein was used as the antigen.
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亚型
- IgG
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anti-Contactin 1 (CNTN1) (AA 250-350) antibody
CNTN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Contactin 1 (CNTN1) antibodyCNTN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Contactin 1 (CNTN1) (AA 585-870) antibodyVerified CNTN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Contactin 1 (CNTN1) (Internal Region) antibodyVerified CNTN1 适用: 人, 大鼠, 小鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Contactin 1 (CNTN1) antibodyCNTN1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Contactin 1 (CNTN1) (AA 947-961), (Extracellular) antibodyCNTN1 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Contactin 1 (CNTN1) (N-Term) antibodyCNTN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Contactin 1 (CNTN1) (AA 686-866) antibodyCNTN1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Contactin 1 (CNTN1) (AA 301-350) antibodyCNTN1 适用: 人, 大鼠, 小鼠, 豚鼠, Pig, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Contactin 1 (CNTN1) (N-Term) antibodyCNTN1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- Contactin 1 (CNTN1)
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别名
- Contactin 1
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背景
- FUNCTION: Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth. SUBUNIT: Monomer. Interacts with CNTNAP1 in cis form. Binds to the carbonic-anhydrase like domain of protein-tyrosine phosphatase zeta. Interacts with NOTCH1 and TNR. SUBCELLULAR LOCATION: Cell membrane, Lipid-anchor GPI-anchor. MISCELLANEOUS: F3 shares with L1 N-CAM MAG and other cell adhesion molecules from nervous tissue the L2/HNK-1 carbohydrate epitope. TISSUE SPECIFICITY: Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung pancreas kidney and skeletal muscle.
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UniProt
- Q12860
抗原
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