ASIC3 抗体 (AA 50-100)
Quick Overview for ASIC3 抗体 (AA 50-100) (ABIN571604)
抗原
See all ASIC3 (ACCN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-100
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原理
- Rabbit antibody to extracellular ASIC3 (50-100)
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特异性
- Specific for ASIC3.
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交叉反应
- 小鼠, 大鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from AA 50-100 of rat ASIC3 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse.
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亚型
- IgG
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anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) (AA 62-320) antibody
ACCN3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) (AA 53-102) antibodyACCN3 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) (N-Term) antibodyACCN3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) (N-Term) antibodyACCN3 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) (AA 2-16), (Intracellular) antibodyACCN3 适用: 大鼠 WB, IHC, IF 宿主: 豚鼠 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) (AA 1-549) antibodyACCN3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) (AA 2-16), (Intracellular) antibodyACCN3 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) (Internal Region) antibodyACCN3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
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别名
- ASIC3
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背景
- FUNCTION: Cation channel with high affinity for sodium which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties. SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins (Probable). Interacts with STOM and DLG4. Interacts with LIN7B MAGI1/BAIAP1 GOPC and ACCN1. SUBCELLULAR LOCATION: Cell membrane, Multi-pass membrane protein. Cytoplasm. Note: Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4. In part cytoplasmic in cochlea cells. TISSUE SPECIFICITY: Expressed by sensory neurons. Strongly expressed in brain spinal chord lung lymph nodes kidney pituitary heart and testis. DEVELOPMENTAL STAGE: Expressed in fetal tissues expression increases in lung and kidney adult tissues.
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UniProt
- O35240
抗原
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