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ASIC3 抗体 (N-Term)

ACCN3 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042990
发货至: 中国
  • 抗原 See all ASIC3 (ACCN3) 抗体
    ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
    抗原表位
    • 14
    • 11
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 56-73, N-Term
    适用
    • 36
    • 10
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 37
    • 3
    • 1
    克隆类型
    • 41
    多克隆
    标记
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASIC3 antibody is un-conjugated
    应用范围
    • 27
    • 23
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Acid-sensing ion channel 3(ASIC3) detection. Tested with WB in Human,Mouse,Rat.
    序列
    FLYQVAERVR YYREFHHQ
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Acid-sensing ion channel 3(ASIC3) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: acid-sensing(proton-gated) ion channel 3
    Protein Name: Acid-sensing ion channel 3
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3(56-73aa FLYQVAERVRYYREFHHQ), different from the related rat and mouse sequences by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ACCN3 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Schuhmacher, Callejo, Srivats, Smith: "Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers." in: The Journal of biological chemistry, Vol. 293, Issue 5, pp. 1756-1766, (2018) (PubMed).

  • 抗原
    ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
    别名
    ASIC3 (ACCN3 产品)
    别名
    ACCN3 antibody, Accn3 antibody, DRASIC antibody, SLNAC1 antibody, TNaC1 antibody, AW742291 antibody, TNAC1 antibody, amiloride-sensitive cation channel 3 antibody, acid sensing ion channel subunit 3 antibody, acid-sensing (proton-gated) ion channel 3 antibody, ACCN3 antibody, ASIC3 antibody, Asic3 antibody
    背景
    ASIC3(Acid-Sensing Ion Channel3), also known as TESTIS SODIUM CHANNEL 1(TNAC1) or DORSAL ROOT ACID-SENSING ION CHANNEL(DRASIC), is a protein that in humans is encoded by the ASIC3 gene. ASIC3 belongs to a family of acid-sensing channel proteins that are structurally related to epithelial sodium channel proteins and support acid-activated membrane currents. By radiation hybrid analysis, de Weille et al.(1998) mapped the ACCN3 gene to chromosome 7q35. De Weille et al.(1998) found that human ASIC3 supported an H(+)-gated cation current in COS cells with kinetics similar to those of rat Asic3. Babinski et al.(1999) expressed homomeric human ASIC3 channels in Xenopus oocytes and found that rapid reduction in extracellular pH resulted in a biphasic response characterized by a fast and rapidly desensitizing current followed by a slow and sustained current that returned to baseline only on return to physiologic pH .

    Synonyms: ACCN 3 antibody|ACCN3 antibody|ACCN3_HUMAN antibody|Acid sensing ion channel 3 antibody|Acid-sensing ion channel 3 antibody|Amiloride sensitive cation channel 3 antibody|Amiloride sensitive cation channel 3 testis antibody|Amiloride-sensitive cation channel 3 antibody|ASIC 3 antibody|ASIC3 antibody|DRASIC antibody|hASIC 3 antibody|hASIC3 antibody|hTNaC 1 antibody|hTNaC1 antibody|Modulatory subunit of ASIC 2a antibody|Modulatory subunit of ASIC2a antibody|Neuronal amiloride sensitive cation channel 3 antibody|Neuronal amiloride-sensitive cation channel 3 antibody|Proton gated cation channel subunit antibody|SLNAC 1 antibody|SLNAC1 antibody|Testis sodium channel 1 antibody|TNaC 1 antibody|TNaC1 antibody
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