ASIC3 抗体 (N-Term)
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北京 101111
Quick Overview for ASIC3 抗体 (N-Term) (ABIN2776167)
抗原
See all ASIC3 (ACCN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- ACCN3 Antibody - N-terminal region
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序列
- VATFLYQVAE RVRYYREFHH QTALDERESH RLIFPAVTLC NINPLRRSRL
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预测反应
- Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 100%, Mouse: 87%, Pig: 87%, Rabbit: 87%, Rat: 87%
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产品特性
- This is a rabbit polyclonal antibody against ACCN3. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACCN3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094502
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
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别名
- ACCN3
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背景
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Background Information: ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
Gene Name: Acid-sensing (proton-gated) ion channel 3
Alternative Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
Protein Name: Acid-sensing ion channel 3
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分子量
- 58kDa
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基因ID
- 9311
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NCBI登录号
- NP_004760
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UniProt
- Q9UHC3
抗原
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