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CCR3 抗体

This anti-CCR3 antibody is a 兔 多克隆 antibody detecting CCR3 in WB 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5708366
发货至: 中国

Quick Overview for CCR3 抗体 (ABIN5708366)

抗原

See all CCR3 抗体
CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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  • 25
  • 1
多克隆

标记

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This CCR3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 纯化方法

    Antigen affinity purified

    免疫原

    Amino acids MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMA were used as the immunogen for the CCR3 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CCR3 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the CCR3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

    别名

    CCR3

    背景

    C-C chemokine receptor type 3, also called CCR3 or CKR3 is a protein that in humans is encoded by the CCR3 gene. The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. Alternatively spliced transcript variants have been described.

    UniProt

    P51677
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