TNFSF15 抗体
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北京 101111
Quick Overview for TNFSF15 抗体 (ABIN5708010)
抗原
See all TNFSF15 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified
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纯度
- Protein A affinity chromatography
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免疫原
- A full length human recombinant protein was used as the immunogen for this recombinant TNFSF15 antibody.
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亚型
- IgG kappa
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 161-251) antibody
TNFSF15 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC, StM 宿主: 兔 Monoclonal VEGI-2052R unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rVEGI-1283 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 67-251) antibodyTNFSF15 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal VEGI-1283 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC (p) 宿主: 兔 Monoclonal VEGI-2052R unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (C-Term) antibodyTNFSF15 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) antibodyTNFSF15 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 70-230) antibodyTNFSF15 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Titration of the recombinant TNFSF15 antibody may be required for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL,Prediluted IHC only format : incubate for 30 min at RT (1) -
限制
- 仅限研究用
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant TNFSF15 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
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别名
- TNFSF15 / VEGI / TL1A
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背景
- TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A/TNFSF15/VEGI has been reported as a marker of poor prognosis in breast cancer.
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基因ID
- 9966
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途径
- Positive Regulation of Endopeptidase Activity, Autophagy
抗原
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