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CD27 抗体

This anti-CD27 antibody is a 兔 单克隆 antibody detecting CD27 in IHC (p). Suitable for 人.
产品编号 ABIN5707991
发货至: 中国

Quick Overview for CD27 抗体 (ABIN5707991)

抗原

See all CD27 抗体
CD27 (CD27 Molecule (CD27))

适用

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克隆类型

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单克隆

标记

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This CD27 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CDLA27-1R
  • 纯化方法

    Purified

    纯度

    Protein A affinity chromatography

    免疫原

    Human CD27 protein was used as the immunogen for the recombinant CD27 antibody.

    亚型

    IgG kappa
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the recombinant CD27 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

    限制

    仅限研究用
  • 缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant CD27 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    CD27 (CD27 Molecule (CD27))

    别名

    CD27

    背景

    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [Wiki]

    途径

    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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